Studies on uracils: an efficient method for the synthesis of novel 1-allyl-6-(1 ',2 ',3 '-triazolyl) analogues of HEPT

Authors
Bhuyan, PJ Borah, HN Sandhu, JS
Citation
Pj. Bhuyan et al., Studies on uracils: an efficient method for the synthesis of novel 1-allyl-6-(1 ',2 ',3 '-triazolyl) analogues of HEPT, J CHEM S P1, (21), 1999, pp. 3083-3084
Citations number
24
Categorie Soggetti
Chemistry & Analysis","Organic Chemistry/Polymer Science
Journal title
JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1
ISSN journal
0300922X → ACNP
Issue
21
Year of publication
1999
Pages
3083 - 3084
Database
ISI
SICI code
0300-922X(19991107):21<3083:SOUAEM>2.0.ZU;2-N
Abstract
An efficient synthetic method for preparing novel 1-allyl-6-(1',2',3'-triaz olyl) analogues of HEPT, an anti-HIV reverse transcriptase inhibitor, is re ported. The key step is based upon selective intermolecular cycloaddition o f azide to acetylenes.