Modelling the dynamical baroreflex-feedback control

A comprehensive model of the baroreflex-feedback mechanism regulating the h eart rate, the contractility of the ventricle and the peripheral vascular r esistance is presented. The dynamics of the affector and the effector parts are modelled. For each of the effector organs the steady state behaviour i s used explicitely. Scenarios of heart infarct, mechanical clamping of peri pheral regions and increasing peripheral resistance by drugs are used for v alidation of the dynamics of the model. (C) 2000 Elsevier Science Ltd. All rights reserved.