Lower extremity deep venous thrombosis (LE DVT) is a fairly common conditio
n among brain injury rehabilitation patients, occurring in up to 20% of all
admissions. Upper extremity deep venous thrombosis (UE DVT) is less common
. However, its incidence is expected to increase due to the increasing usag
e of central venous catheterization (CVC). This paper reviews the course of
treatment of a patient with recurrent malignant meningioma who was found t
o have four-extremity deep venous thrombosis on a baseline screening duplex
Doppler ultrasonography at admission to an inpatient brain injury rehabili
tation unit. The need for tumor embolization followed by surgical resection
was felt to preclude chemical prophylaxis for DVT despite the significant
risk factors of; age > 60, immobility, quadriplegia, surgery with anesthesi
a > 30 minutes, and diagnosis of cancer. Aggressive anticoagulation with cl
ose clinical monitoring allowed for successful participation in a full reha
bilitation with only a brief delay. The appropriate treatment of this patie
nt is discussed in light of the latest research findings. Recommendations f
or future treatment protocols and research are made.