Pairwise use of complexity-generating reactions in diversity-oriented organic synthesis

Authors
Lee, DS Sello, JK Schreiber, SL
Citation
Ds. Lee et al., Pairwise use of complexity-generating reactions in diversity-oriented organic synthesis, ORG LETT, 2(5), 2000, pp. 709-712
Citations number
37
Categorie Soggetti
Organic Chemistry/Polymer Science
Journal title
ORGANIC LETTERS
ISSN journal
15237060 → ACNP
Volume
2
Issue
5
Year of publication
2000
Pages
709 - 712
Database
ISI
SICI code
1523-7060(20000309)2:5<709:PUOCRI>2.0.ZU;2-#
Abstract
[GRAPHICS] Two pairs of complexity-generating reactions with an essential product-subs trate relationship along a synthetic pathway are demonstrated, This pathway illustrates a key element in a planning algorithm for diversity-oriented s ynthesis, This element facilitates the efficient synthesis of structurally complex compounds, and it can be integrated with ones that provide structur ally diverse compounds.