Acute basophilic leukemia presenting with abnormal liver function tests and the absence of blast cells in the peripheral blood

Authors
Scolyer, RA Brun, M D'Rozario, J Webb, M
Citation
Ra. Scolyer et al., Acute basophilic leukemia presenting with abnormal liver function tests and the absence of blast cells in the peripheral blood, PATHOLOGY, 32(1), 2000, pp. 52-55
Citations number
18
Categorie Soggetti
Medical Research Diagnosis & Treatment
Journal title
PATHOLOGY
ISSN journal
00313025 → ACNP
Volume
32
Issue
1
Year of publication
2000
Pages
52 - 55
Database
ISI
SICI code
0031-3025(200002)32:1<52:ABLPWA>2.0.ZU;2-H
Abstract
Acute basophilic leukemia is an uncommon form of acute leukemia, rarely occ urring as a de novo disease. We describe a case of de novo acute basophilic leukemia occurring in a 47-year-old man who presented with abnormal liver function tests in the absence of leukemic infiltration of the liver. We pos tulate that this presentation occurred as a consequence of pathophysiologic al features of the malignant basophilic blast cells.