An interaction of word frequency and word regularity has typically been obs
erved in naming and lexical decision experiments in which, in addition to a
n overall effect of word frequency, responses to low-frequency exception wo
rds are slower than those to low-frequency regular words, while no such dif
ference occurs with high-frequency words. The only eye movement study to ex
amine this effect in reading (Inhoff & Topolski, 1994) reported only transi
ent effects of regularity. In the present experiment, we examined the frequ
ency x regularity interaction using different stimuli than these of Inhoff
and Topolski and also varied the parafoveal preview of the target word prio
r to fixation. When the preview was valid, the frequency x regularity inter
action appeared. However, with an invalid preview, the effect of regularity
disappeared. The results suggest that the activation of phonological codes
is a very early component of reading.