Arabidopsis cytochrome P450s that catalyze the first step of tryptophan-dependent indole-3-acetic acid biosynthesis

Authors
Hull, AK Vij, R Celenza, JL
Citation
Ak. Hull et al., Arabidopsis cytochrome P450s that catalyze the first step of tryptophan-dependent indole-3-acetic acid biosynthesis, P NAS US, 97(5), 2000, pp. 2379-2384
Citations number
40
Categorie Soggetti
Multidisciplinary
Journal title
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
ISSN journal
00278424 → ACNP
Volume
97
Issue
5
Year of publication
2000
Pages
2379 - 2384
Database
ISI
SICI code
0027-8424(20000229)97:5<2379:ACPTCT>2.0.ZU;2-M
Abstract
Plants synthesize numerous secondary metabolites that are used as developme ntal signals or as defense against pathogens, Tryptophan (Trp)-derived seco ndary metabolites include camalexin, indole glucosinolates, and indole-3-ac etic acid (IAA); however, the steps in their synthesis from Trp or its prec ursors remain unclear. We have identified two Arabidopsis cytochrome P450s (CYP79B2 and CYP79B3) that can convert Trp to indole-3-acetaldoxime (IAOx), a precursor to IAA and indole glucosinolates.