Past occupational exposure to asbestos among men in France

Objectives This study aimed at reconstructing changes in the frequency and levels of occupational asbestos exposure in France over the past century. Methods Work histories were collected during 11 population-based case-refer ent studies recently carried out in France, and an asbestos-specific job-ex posure matrix including 10 625 jobs was used to estimate indices of past oc cupational asbestos exposure. The results were estimated from a sample of 4 287 subjects, bootstrapped 200 rimes. Results The distribution of socioeconomic categories within the sample was compared with that of the general population in 1954, 1962, 1968, 1975, and 1982. The proportion of blue-collar workers was similar. The highest propo rtion of exposed subjects was found between 1950 and 1980. Around 10% of ea ch 10-year age class was exposed to asbestos. For those born in 1930-1939, 15.2% was exposed between the ages of 20 and 29 years. For each age class b orn in 1900-1939, the proportion exposed at least once by 60 years of age r anged from 18.2% to 24.5% and, of those exposed, the cumulative duration of exposure ranged from 11.3 to 15.4 years by the age of 60 years. A populati on exposure index showed that the heaviest exposure occurred between 1960 a nd 1970 and that the age classes born between 1920 and 1929 were the most h eavily exposed. Time trends showed that the mean value of this index for th e men aged 20-59 years reached a peak in the 1960s and then decreased. Conclusions This study presents data of reasonable validity about occupatio nal asbestos exposure in France and its trends over the past century; the d ata are being used to forecast the development of male mortality from mesot helioma in France.