Diastereoselective synthesis of protected 2,3-dihydroxynitriles from 2-hydroxy acids

Authors
Hutin, P Larcheveque, M
Citation
P. Hutin et M. Larcheveque, Diastereoselective synthesis of protected 2,3-dihydroxynitriles from 2-hydroxy acids, SYNTHESIS-S, (2), 2000, pp. 220-222
Citations number
16
Categorie Soggetti
Chemistry & Analysis","Organic Chemistry/Polymer Science
Journal title
SYNTHESIS-STUTTGART
ISSN journal
00397881 → ACNP
Issue
2
Year of publication
2000
Pages
220 - 222
Database
ISI
SICI code
0039-7881(200002):2<220:DSOP2F>2.0.ZU;2-G
Abstract
The DIBAL-H reduction of dioxolanones 2 prepared from 2-hydroxy acids follo wed by addition of acetone cyanohydrin affords the syn 2,3-dihydroxynitrile s in high enantiomerical purities.