A novel method for preparation of trifluoromethyl substituted 2,3-dihydro-1,4-diazepine and benzimidazole

Authors
Chu, QL Wang, YL Zhu, SZ
Citation
Ql. Chu et al., A novel method for preparation of trifluoromethyl substituted 2,3-dihydro-1,4-diazepine and benzimidazole, SYN COMMUN, 30(4), 2000, pp. 677-687
Citations number
12
Categorie Soggetti
Organic Chemistry/Polymer Science
Journal title
SYNTHETIC COMMUNICATIONS
ISSN journal
00397911 → ACNP
Volume
30
Issue
4
Year of publication
2000
Pages
677 - 687
Database
ISI
SICI code
0039-7911(2000)30:4<677:ANMFPO>2.0.ZU;2-5
Abstract
Ethylenediamine reacted readily with 4-ethoxy-1,1,1-trifluoro-3-butene-2-on e to form 5-trifluoromethyl-2,3-dihydro-1,4-diazepine in good yield. Under the same reaction conditions o-phenylene diamine gave 2-trifluoromethyl ben zimidazole and benzimidazole.