Intramolecular Michael reactions by iron(III) catalysis

Authors
Christoffers, J Oertling, H
Citation
J. Christoffers et H. Oertling, Intramolecular Michael reactions by iron(III) catalysis, TETRAHEDRON, 56(10), 2000, pp. 1339-1344
Citations number
31
Categorie Soggetti
Chemistry & Analysis","Organic Chemistry/Polymer Science
Journal title
TETRAHEDRON
ISSN journal
00404020 → ACNP
Volume
56
Issue
10
Year of publication
2000
Pages
1339 - 1344
Database
ISI
SICI code
0040-4020(20000303)56:10<1339:IMRBIC>2.0.ZU;2-#
Abstract
Seven-membered ring annulation is achieved by an intramolecular Michael rea ction catalyzed by iron(III) chloride hexahydrate. Reaction conditions are mild and non-basic, and chemo- and stereoselectivity is excellent. Contrast ingly, this method fails for a 17-membered ring annulation. (C) 2000 Elsevi er Science Ltd. All rights reserved.