Lh. Hu et Ky. Sim, Sampsoniones A-M, a unique family of caged polyprenylated benzoylphloroglucinol derivatives, from Hypericum sampsonii, TETRAHEDRON, 56(10), 2000, pp. 1379-1386
Further thorough investigation of the ethanolic extract of the aerial parts
of Hypericum sampsonii has yielded sampsoniones K-M which together with th
e earlier isolated sampsoniones A-J form a unique family of related polypre
nylated benzoylphloroglucinol derivatives formed by complex cyclisations of
prenyl groups. The structures of these cage compounds have been elucidated
by extensive studies of various spectrometric techniques. The 13 metabolit
es, some of which are bioactive, are probably biosynthesized from a simple
common benzoylphloroglucinol precursor. (C) 2000 Elsevier Science Ltd. All
rights reserved.