Sampsoniones A-M, a unique family of caged polyprenylated benzoylphloroglucinol derivatives, from Hypericum sampsonii

Authors
Citation
Lh. Hu et Ky. Sim, Sampsoniones A-M, a unique family of caged polyprenylated benzoylphloroglucinol derivatives, from Hypericum sampsonii, TETRAHEDRON, 56(10), 2000, pp. 1379-1386
Citations number
21
Categorie Soggetti
Chemistry & Analysis","Organic Chemistry/Polymer Science
Journal title
TETRAHEDRON
ISSN journal
00404020 → ACNP
Volume
56
Issue
10
Year of publication
2000
Pages
1379 - 1386
Database
ISI
SICI code
0040-4020(20000303)56:10<1379:SAAUFO>2.0.ZU;2-E
Abstract
Further thorough investigation of the ethanolic extract of the aerial parts of Hypericum sampsonii has yielded sampsoniones K-M which together with th e earlier isolated sampsoniones A-J form a unique family of related polypre nylated benzoylphloroglucinol derivatives formed by complex cyclisations of prenyl groups. The structures of these cage compounds have been elucidated by extensive studies of various spectrometric techniques. The 13 metabolit es, some of which are bioactive, are probably biosynthesized from a simple common benzoylphloroglucinol precursor. (C) 2000 Elsevier Science Ltd. All rights reserved.