Macrophyllidimers A and B, two novel sesquiterpene dimers in whose structur
es the two sesquiterpene units are connected by a C-C bond directly, have b
een isolated from the bark of Inula macrophylla. Their structures were dete
rmined on the basis of spectral evidence. The structure of macrophyllidimer
B was finally confirmed by X-ray analysis. The possible biosynthetic pathw
ays of macrophyllidimers A and B are also discussed. (C) 2000 Elsevier Scie
nce Ltd. All rights reserved.