A three-step and enantioselective synthesis of (-)-(S)- or (+)-(R)-2-(furan-3-yl)-3,6-dihydro-2H-pyrans

Authors
de Rosa, M Solladie-Cavallo, A Scettri, A
Citation
M. De Rosa et al., A three-step and enantioselective synthesis of (-)-(S)- or (+)-(R)-2-(furan-3-yl)-3,6-dihydro-2H-pyrans, TETRAHEDR L, 41(10), 2000, pp. 1593-1596
Citations number
11
Categorie Soggetti
Chemistry & Analysis","Organic Chemistry/Polymer Science
Journal title
TETRAHEDRON LETTERS
ISSN journal
00404039 → ACNP
Volume
41
Issue
10
Year of publication
2000
Pages
1593 - 1596
Database
ISI
SICI code
0040-4039(20000304)41:10<1593:ATAESO>2.0.ZU;2-1
Abstract
Enantiomerically enriched (3-furyl)-2-pyran derivatives, key-intermediates in the synthesis of the pharmacophoric pyranofuranone system of the bioacti ve natural products manoalide and cacospongionolide B, are easily accessibl e by a rapid sequence involving a chiral allylation and a ring closing meta thesis reaction. (C) 2000 Elsevier Science Ltd. All rights reserved.