Objectives. To investigate the value of the renal resistive index (RI) in t
he identification of acute renal obstruction in pregnant women.
Methods. The study included 22 pregnant women with acute unilateral uretera
l obstruction due to a stone disease (group A), 71 normotensive pregnant pa
tients without loin pain (group B), and 20 nonpregnant women of child-beari
ng age with both kidneys normal (group C). All patients underwent Doppler u
ltrasound (DUS) with determination of the Ri and the difference between the
RI of the corresponding and contralateral kidney (Delta RI). The RI and De
lta RI was considered positive for obstruction with a value of 0.70 or grea
ter and 0.04 or greater, respectively. Ureteral obstruction was confirmed b
y several clinical, radiologic, and endoscopic findings. The sensitivity, s
pecificity, and overall accuracy of RI and Delta RI for the diagnosis of ac
ute unilateral ureteral obstruction were calculated.
Results. in group A, kidneys with ureteral obstruction (n = 22) had a mean
RI of 0.69 +/- 0.03; the contralateral normal kidneys (n = 22) had a mean R
I of 0.63 +/- 0.03, a significant difference (P < 0.0001). The mean RI of a
il kidneys in group B (n = 142) and all kidneys in group C (n = 40) was 0.6
4 +/- 0.05 and 0.62 +/- 0.04, respectively; the difference was not statisti
cally significant. A comparison between the mean RI of the normal kidneys o
f group A and ail the kidneys of groups B and C revealed no significant dif
ference. The mean RI of the obstructed kidneys in group A was significantly
higher than the mean RI of all the kidneys in groups 5 and C. Similarly, t
he mean Delta RI of group A was significantly higher than the mean Delta RI
of groups B and C (0.06 +/- 0.01 versus 0.006 +/- 0.003 versus 0.006 +/- 0
.004, respectively). The RI was sensitive in 45%, specific in 91%, and accu
rate in 87%. The corresponding values for Delta RI were 95%, 100%, and 99%.
Conclusions. The Delta RI is a sensitive and specific test that can replace
intravenous urography in the diagnosis of acute unilateral ureteral obstru
ction in pregnant women. (C) 2000, Elsevier Science Inc.