Bilateral juxtafoveolar telangiectasis in monozygotic twins

PURPOSE: To report the clinical and angiographic features of two monozygoti c twins affected by bilateral group 2 idiopathic juxtafoveolar telangiectas is. METHOD: Case reports. RESULTS: Two 64-year-old women, who were identical twins, were suffering fr om visual loss, One twin had suffered from visual loss for 1 year and had a visual acuity of 20/25 in both eyes, and the other twin had suffered for 2 years and had a visual acuity of 20/30 in both eyes. Fluorescein angiograp hy disclosed similar fundus features, An analogous area of capillary telang iectasis and leakage was observed in the right macula, where no intraretina l pigment was seen; the left macula showed a similar amount of intraretinal pigment associated with tiny right-angle venules and minimal leakage. CONCLUSION: This observation raises the issue of genetic influences in the pathogenesis of this disease; (C) 2000 by Elsevier Science Inc. All. rights reserved.