K. Wong et al., A comparison of patient-controlled epidural analgesia following gynaecological surgery with and without a background infusion, ANAESTHESIA, 55(3), 2000, pp. 212-216
Citations number
9
Categorie Soggetti
Aneshtesia & Intensive Care","Medical Research Diagnosis & Treatment
We conducted a randomised, controlled study to investigate the effect of ad
ding a background infusion to patient-controlled epidural analgesia for pos
toperative pain relief. Forty-two patients scheduled for elective lower abd
ominal gynaecological surgery received patient-controlled epidural analgesi
a postoperatively using a mixture of 0.2% ropivacaine and 2.0 mu g.ml(-1) f
entanyl. Patients in group B (n = 20) were given a background infusion of 5
ml.h(-1), whereas those in group N (n = 21) were not. There was no differe
nce in pain scores or patient satisfaction scores between the two groups. P
atients in group B had a higher total drug consumption (156.8 +/- 34.8 mi v
s. 89.5 +/- 41.0 mi, p < 0.0001) and incidence of side-effects (71.4% vs. 3
0.0%; p = 0.007). Motor blockade during the 24-h study period was also grea
ter in group B (median [range] area under the curve 7.5 [0.0-39.0] h vs. 3.
0 [0.0-36.0] h; p = 0.035). We conclude that the addition of a background i
nfusion to patient-controlled epidural anaesthesia is not recommended as it
confers no additional benefits.