BACKGROUND: The purpose of this study was to search for a more effecti
ve transfusion-monitoring system than the existing system of retrospec
tive peer review. STUDY DESIGN AND METHODS: This research used a study
-control, preintervention and postintervention design, to evaluate the
effectiveness of a prospective physician self-audit transfusion-monit
oring system that functioned without the direct involvement of transfu
sion service physicians. This research also evaluated the effectivenes
s of issuing to physicians a memo with transfusion guidelines. Three p
rocess indicators were used to assess physician behavior at various st
ages of the blood-ordering process: 1) the number of crossmatches orde
red per admission, 2) the transfusion-to-crossmatch ratio, and 3) the
number of blood units returned to the laboratory after physician self-
auditing. The study used two outcome indicators to reflect overall blo
od utilization: 1) the percentage of patients who received red cell tr
ansfusions and 2) the number of blood units transfused per recipient e
ach month. RESULTS: Tile prospective physician self-audit system imple
mented at the study hospital did not reverse physician transfusion dec
isions, and the process of issuing to physicians a memo with transfusi
on guidelines at the control hospital failed to reduce blood usage. Ho
wever, a transient reduction in blood utilization was observed at the
study hospital. CONCLUSION: The reduction was hypothesized to be due t
o a Hawthorne effect, in which observed behavior is affected by the su
bject's awareness of the research study.