Validation of HCV-NAT assays and experience with NAT application for bloodscreening in Germany

Authors
Nubling, CM Chudy, M Lower, J
Citation
Cm. Nubling et al., Validation of HCV-NAT assays and experience with NAT application for bloodscreening in Germany, BIOLOGICALS, 27(4), 1999, pp. 291-294
Categorie Soggetti
Microbiology
Journal title
BIOLOGICALS
ISSN journal
10451056 → ACNP
Volume
27
Issue
4
Year of publication
1999
Pages
291 - 294
Database
ISI
SICI code
1045-1056(199912)27:4<291:VOHAAE>2.0.ZU;2-Y
Abstract
Validation of HCV-NAT assays is an important prerequisite for the use of NA T for screening plasma or blood donations. The main NAT features to be vali dated are specificity, detection limit and robustness. Preliminary experien ce in Germany obtained with different methodical and logistic approaches sh ows the feasibility of HCV-NAT as a screening test for blood donations. (C) 1999 The International Association for Biologicals.