In 1995, the WHO Regional Office for Africa launched a logistics project to
address the four main areas of immunization logistics: the cold chain, tra
nsport, vaccine supply and quality, and the safety of injections in the cou
ntries of the region. The impact of this logistic approach on immunization
injection safety was evaluated through surveys of injection procedures and
an analysis of the injection materials (e.g. sterilizable or disposable syr
inges) chosen by the Expanded Programme on Immunization (EPI) and those act
ually seen to be used. Re-use of injection materials without sterilization,
accidental needle-stick injuries among health care workers, and injection-
related abscesses in patients were common in countries in the WHO African R
egion. Few health centres used time-steam saturation-temperature (TST) indi
cators to check the quality of sterilization and, in many centres, the inje
ction equipment was boiled instead of being steam sterilized. Facilities fo
r the proper disposal of used materials were rarely present. Although the o
fficial EPI choice was to use sterilizable equipment, use of a combination
of sterilizable and disposable equipment was observed in the field. Unsafe
injection practices in these countries were generally due to a failure to i
ntegrate nursing practices and public awareness with injection safety issue
s, and an absence of the influence of EPI managers on health care service d
elivery. Holistic rather than logistic approaches should be adopted to achi
eve safe injections in immunization, in the broader context of promoting sa
fe vaccines and safety of all injections.