Notch signaling in T cell development

Authors
Deftos, ML Bevan, MJ
Citation
Ml. Deftos et Mj. Bevan, Notch signaling in T cell development, CURR OP IM, 12(2), 2000, pp. 166-172
Citations number
47
Categorie Soggetti
Immunology
Journal title
CURRENT OPINION IN IMMUNOLOGY
ISSN journal
09527915 → ACNP
Volume
12
Issue
2
Year of publication
2000
Pages
166 - 172
Database
ISI
SICI code
0952-7915(200004)12:2<166:NSITCD>2.0.ZU;2-D
Abstract
Notch signaling regulates cell fate decisions during development. Recent ex periments suggest that Notch signaling is essential for initial commitment to the T cell lineage and may function together with signals from the pre-T CR and the TCR to regulate subsequent steps of T cell development.