ITA
ENG

GLUCOPYRANOSE SPIROHYDANTOINS - SPECIFIC INHIBITORS OF GLYCOGEN-PHOSPHORYLASE

Authors

DELAFUENTE C KRULLE TM WATSON KA GREGORIOU M JOHNSON LN TSITSANOU KE ZOGRAPHOS SE OIKONOMAKOS NG FLEET GWJ

Citation

C. Delafuente et al., GLUCOPYRANOSE SPIROHYDANTOINS - SPECIFIC INHIBITORS OF GLYCOGEN-PHOSPHORYLASE, Synlett, (5), 1997, pp. 485

Citations number

Categorie Soggetti

Chemistry Inorganic & Nuclear

Journal title

Synlett → ACNP

ISSN journal

09365214

Issue

Year of publication

1997

Database

ISI

SICI code

0936-5214(1997):5<485:GS-SIO>2.0.ZU;2-V

Abstract

A short synthesis of the spirohydantoin of glucopyranose Ip [a potent and specific inhibitor of glycogen phosphorylase], together with its i nactive anomer 1 alpha, from a readily available heptonolactone is des cribed; this is the first synthesis of a spirohydantoin of a pyranose in which the pyranose ring is formed after the hydantoin ring.