Functional derivatives of 5-benzo[1,3]-5-yl-1-methyl-1H-imidazole-2-carbaldehyde and evaluation of leishmanicidal activity

Authors
Vanelle, P Meuche, J Maldonado, J Crozet, MP Delmas, F Timon-David, P
Citation
P. Vanelle et al., Functional derivatives of 5-benzo[1,3]-5-yl-1-methyl-1H-imidazole-2-carbaldehyde and evaluation of leishmanicidal activity, EUR J MED C, 35(1), 2000, pp. 157-162
Citations number
15
Categorie Soggetti
Chemistry & Analysis
Journal title
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
ISSN journal
02235234 → ACNP
Volume
35
Issue
1
Year of publication
2000
Pages
157 - 162
Database
ISI
SICI code
0223-5234(200001)35:1<157:FDO5>2.0.ZU;2-U
Abstract
New imidazole derivatives were obtained after subjecting 5-benzol[1,3]dioxo l-5-yl-1-methyl-1H-imidazole-2-carbaldehyde to a Knoevenagel reaction. Some of these compounds exhibit significant in vitro leishmanicidal activity. ( C) 2000 Editions scientifiques et medicales Elsevier SAS.