Lamivudine for the prevention of hepatitis B virus reactivation during autologous stem cell transplantation. A case report

Authors
Silvestri, F Sperotto, A Ermacora, A Fanin, R Damiani, D Baccarani, M
Citation
F. Silvestri et al., Lamivudine for the prevention of hepatitis B virus reactivation during autologous stem cell transplantation. A case report, HAEMATOLOG, 85(3), 2000, pp. 327-329
Citations number
8
Categorie Soggetti
Cardiovascular & Hematology Research
Journal title
HAEMATOLOGICA
ISSN journal
03906078 → ACNP
Volume
85
Issue
3
Year of publication
2000
Pages
327 - 329
Database
ISI
SICI code
0390-6078(200003)85:3<327:LFTPOH>2.0.ZU;2-T
Abstract
Reactivation of hepatitis B virus (HBV) is a frequent complication during c hemotherapy; it may give rise to hepatitis, hepatic failure and death and m ay prevent further chemotherapy from being administered. We present a case in which the use of lamivudine allowed autologous stem cell transplantation to be performed after a hepatitis flare-up, suggesting a possible role for this drug in preventing HBV reactivation during chemotherapy.