Granular cell tumors of the colon - Report of a case and review of the literature

Granular cell tumors are uncommon, usually benign tumors that can be locate d anywhere in the body. They commonly occur in the oral cavity and in subcu taneous tissue. In the gastrointestinal tract, granular cell tumors are unc ommon and are quits rare in the colon. To date, 55 patients diagnosed with granular cell tumors of the colon have been reported in the literature, onl y 15 had multiple tumors. We describe the case of a 38-year-old man with a family history of colon cancer who was diagnosed with multiple colonic gran ular cell tumors after a screening colonoscopy. This seems to be the first report of this type. However, in our patient, the diagnosis of colonic gran ular cell tumors was incidental and there is no data that correlates adenom as or colorectal cancer with granular cell tumors of the colon. Finally, si nce granular cell tumors are usually benign, we suggest a conservative appr oach to patients with multiple granular cell tumors of the colon by means o f endoscopic resection and a strict endoscopic follow-up.