Use of calibrated viral load standards for group m subtypes of human immunodeficiency virus type 1 to assess the performance of viral RNA quantitation tests

Authors
Jagodzinski, LL Wiggins, DL McManis, JL Emery, S Overbaugh, J Robb, M Bodrug, S Michael, NL
Citation
Ll. Jagodzinski et al., Use of calibrated viral load standards for group m subtypes of human immunodeficiency virus type 1 to assess the performance of viral RNA quantitation tests, J CLIN MICR, 38(3), 2000, pp. 1247-1249
Citations number
28
Categorie Soggetti
Clinical Immunolgy & Infectious Disease",Microbiology
Journal title
JOURNAL OF CLINICAL MICROBIOLOGY
ISSN journal
00951137 → ACNP
Volume
38
Issue
3
Year of publication
2000
Pages
1247 - 1249
Database
ISI
SICI code
0095-1137(200003)38:3<1247:UOCVLS>2.0.ZU;2-T
Abstract
Optimal management of human immunodeficiency virus type 1 (HIV-1) disease r equires accurate quantitation of viral RNA concentrations in plasma. Eviden ce for increasing geographic intermixing of HIV-1 subtypes makes equivalent quantitation of all subtypes essential. The performances of six quantitati ve viral RNA tests are described, for the first time, with calibrated viral isolates of diverse subtypes.