Population genetics of two tetranucleotide repeats (UGB and D3S1349): a preliminary study in Galicia, Spain

The polymorphism of two tetranucleotide repeats, UGB and D3S1349 in the pop ulation of Galicia, Spain was carried out. Up to 7 and 8 alleles respective ly were found, which determine values of H = 0.820 and H = 0.808 for these two STRs. A non-isotopic technique using thin layer polyacrylamide gel elec trophoresis followed by silver staining, for the screening of both systems, is presented and discussed. Formal genetic studies from 51 meioses are con cordant with an autosomal co-dominant way of inheritance of these systems.