Many clinical studies have emphasized the role of the hamstrings and the il
iotibial band on knee mechanics, although few biomechanical studies have in
vestigated it. This study therefore examined two hypotheses: (a) with loadi
ng of the hamstrings, the tibia translates posteriorly and rotates external
ly and the tibial contact pattern shifts anteriorly; furthermore, the chang
es in tibial kinematics alter patellar kinematics and contact: and (b) load
ing the iliotibial band alters the kinematics and contact pattern of the ti
biofemoral joint similarly to loading the hamstrings, and loading the iliot
ibial band laterally translates the patella and its contact location. Five
cadaveric knee specimens were tested with a specially designed knee-joint t
esting machine in an open-chain configuration. At various flexion angles, t
he knees were tested always with a quadriceps force but with and without a
hamstrings force and with and without an iliotibial band force. The results
support the first hypothesis. Hence, the hamstrings may be important anter
ior and rotational stabilizers of the tibia, a role similar to that of the
anterior cruciate ligament. The results also support the second hypothesis,
although the iliotibial band force had a smaller effect on the tibia than
did the hamstrings force. Both forces also changed patellar kinematics and
contact, demonstrating that these structures should also be considered duri
ng the clinical management of patellar disorders.