Synthesis of the 6,7-bis(2-methoxycarbonyl(1,1-dideutero)ethyl) derivativeof protoporphyrin IX dimethyl ester

Authors
Shim, YK Pandey, RK Smith, KM
Citation
Yk. Shim et al., Synthesis of the 6,7-bis(2-methoxycarbonyl(1,1-dideutero)ethyl) derivativeof protoporphyrin IX dimethyl ester, J PORPHYR P, 4(2), 2000, pp. 185-191
Citations number
43
Categorie Soggetti
Chemistry
Journal title
JOURNAL OF PORPHYRINS AND PHTHALOCYANINES
ISSN journal
10884246 → ACNP
Volume
4
Issue
2
Year of publication
2000
Pages
185 - 191
Database
ISI
SICI code
1088-4246(200003)4:2<185:SOT6D>2.0.ZU;2-W
Abstract
A new total synthesis of a protoporphyrin LY derivative in which the a-meth ylene protons of the 13,17-(2-methoxycarbonylethyl) substituents are regios electively deuterated is described. The deuterated porphyrin was obtained u sing the oxidative cyclization of an a,c-biladiene dihydrobromide. Copyrigh t (C) 2000 John Wiley & Sons, Ltd.