Clay catalyzed conversion of isatoic anhydride to 2-(o-aminophenyl)oxazolines

Authors
Gajare, AS Shaikh, NS Jnaneshwara, GK Deshpande, VH Ravindranathan, T Bedekar, AV
Citation
As. Gajare et al., Clay catalyzed conversion of isatoic anhydride to 2-(o-aminophenyl)oxazolines, J CHEM S P1, (6), 2000, pp. 999-1001
Citations number
18
Categorie Soggetti
Chemistry & Analysis","Organic Chemistry/Polymer Science
Journal title
JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1
ISSN journal
0300922X → ACNP
Issue
6
Year of publication
2000
Pages
999 - 1001
Database
ISI
SICI code
0300-922X(2000):6<999:CCCOIA>2.0.ZU;2-E
Abstract
A simple and environmentally safe procedure for the preparation of 2-(o-ami nophenyl)oxazolines from isatoic anhydride is presented. A series of chiral derivatives of the title compound is prepared in moderate yield via natura l kaolinitic clay catalyzed reactions with optically pure 2-aminoalcohols. Reaction of polymer-supported isatoic anhydride under these conditions with chiral 2-aminoalcohols proceeds to furnish polymer-anchored analogues.