Background and purpose: This comparative cross-sectional and community-base
d study was aimed at defining foot complications in diabetic patients. Thes
e data have not yet been reported for Asian societies.
Methods: Of a population of 3,602 subjects aged 35 years or more in Chin-Sh
an, Taipei, 309 diabetic patients were identified. Two hundred and nineteen
(71%) of those patients were compared to 100 individuals randomly selected
for the nondiabetic control group in the same community.
Results: Three diabetic patients underwent lower extremity amputation and f
our had skin ulcerations. Diabetic patients had a significantly higher prev
alence of peripheral neuropathy (32.4% vs 16%), arterial insufficiency (12.
6% vs 3.0%), and medial arterial calcification (13.6% vs 5.0%), when compar
ed to the nondiabetic controls. The age and sex-adjusted rates of hallux va
lgus, loss of skin hair on the dorsum of the foot, tinea unguium; arterial
insufficiency, medial artery calcification, and peripheral neuropathy were
significantly higher in diabetic than nondiabetic subjects. Aging and hyper
glycemia (> 140 mg/dL) increased the prevalence of foot complications in bo
th groups. Foot complications were also remarkably associated with the dura
tion of diabetes (P = 0.003).
Conclusions: This study shows that diabetes mellitus is associated with an
increased likelihood of foot complications in this geographically defined T
aiwanese population. Patient age and diabetic duration are associated with
the significantly higher prevalence of foot complications.