Low serum IGF-1 and occurrence of osteoporotic fractures in postmenopausalwomen

Authors
Garnero, P Sornay-Rendu, E Delmas, PD
Citation
P. Garnero et al., Low serum IGF-1 and occurrence of osteoporotic fractures in postmenopausalwomen, LANCET, 355(9207), 2000, pp. 898-899
Citations number
5
Categorie Soggetti
General & Internal Medicine","Medical Research General Topics
Journal title
LANCET
ISSN journal
01406736 → ACNP
Volume
355
Issue
9207
Year of publication
2000
Pages
898 - 899
Database
ISI
SICI code
0140-6736(20000311)355:9207<898:LSIAOO>2.0.ZU;2-E
Abstract
The link between serum insulin-like growth factor 1 (IGF-1) and postmenopau sal osteoporosis remains controversial. In this study of healthy postmenopa usal women, decreased serum concentrations of IGF-1 were strongly associate d with an increased risk of osteoporotic fractures independently of bone-mi neral density.