New agents for acute myelogenous leukemia

Authors
Zwiebel, JA
Citation
Ja. Zwiebel, New agents for acute myelogenous leukemia, LEUKEMIA, 14(3), 2000, pp. 488-490
Citations number
24
Categorie Soggetti
Onconogenesis & Cancer Research
Journal title
LEUKEMIA
ISSN journal
08876924 → ACNP
Volume
14
Issue
3
Year of publication
2000
Pages
488 - 490
Database
ISI
SICI code
0887-6924(200003)14:3<488:NAFAML>2.0.ZU;2-V
Abstract
New agents for the treatment of acute myelogenous leukemia are discussed th at reflect different treatment mechanisms. These include histone acetylatio n, angiogenesis inhibition, protein kinase inhibitors, and a novel retinoid . Efficacy and safety in phase I and phase II trials reviewed, as well as t he problems involved in crossing over from treatment of solid tumors to blo od disorders.