Dual streams of auditory afferents target multiple domains in the primate prefrontal cortex

'What' and 'where' visual streams define ventrolateral object and dorsolate ral spatial processing domains in the prefrontal cortex of nonhuman primate s. We looked for similar streams for auditory-prefrontal connections in rhe sus macaques by combining microelectrode recording with anatomical tract-tr acing. Injection of multiple tracers into physiologically mapped regions AL , ML and CL of the auditory belt cortex revealed that anterior belt cortex was reciprocally connected with the frontal pole (area 10), rostral princip al sulcus (area 46) and ventral prefrontal regions (areas 12 and 45), where as the caudal belt was mainly connected with the caudal principal sulcus (a rea 46) and frontal eye fields (area 8a). Thus separate auditory streams or iginate in caudal and rostral auditory cortex and target spatial and non-sp atial domains of the frontal lobe, respectively.