A case of elastofibroma occurring in the sigmoid colon of a 69 year-old wom
an is reported. The woman presented for survey of her gastrointestinal trac
t. Colonoscopy disclosed two polyps in the sigmoid colon, one of which was
clinically considered to be recurrent adenoma. Histologically, the lesion h
ad characteristic eosinophilic fibers and globules, termed elastofibroma fi
bers with hematoxylin and eosin stain. In addition, these elastinophilic ma
terials were digested by elastase. Histological evaluation confirmed the di
agnosis of elastofibroma. Our case might suggest that it is the result of l
ong-term fibrosis after previous endoscopic resection of a sigmoid colonic
adenoma.