A 6-kb cryptic plasmid (pYC; 5919 bp) has been recovered from Yersinia pest
is isolates originating from regions of Yunnan province in China. The seque
nce of pYC was determined, and analysis of the sequence has revealed that t
wo of the plasmid DNA regions (ORFs 10 and 11) are similar to the DinJ1 and
DinJ2 gene products: encoded by Escherichia coli chromosomal DNA. This pla
smid is increasingly harbored by Y. pestis isolates recovered from a domest
ic rodent cycle in the southern regions of the province. Further studies wi
ll determine the origin and function of pYC.