Cross-modal reorganization of human cortical functions

Citation
T. Kujala et al., Cross-modal reorganization of human cortical functions, TRENDS NEUR, 23(3), 2000, pp. 115-120
Citations number
59
Categorie Soggetti
Neurosciences & Behavoir
Journal title
TRENDS IN NEUROSCIENCES
ISSN journal
01662236 → ACNP
Volume
23
Issue
3
Year of publication
2000
Pages
115 - 120
Database
ISI
SICI code
0166-2236(200003)23:3<115:CROHCF>2.0.ZU;2-H
Abstract
Recent technological development has opened fascinating opportunities in re search on cognitive functions of the human brain. For example, cortical rep resentations of sensory functions and their reorganization, which have been studied thoroughly in animals, are far better understood in humans now tha n they were only a decade ago, Hemodynamic and electromagnetic studies have demonstrated that a modality-specific brain area that is totally deprived of its normal sensory input becomes responsive to stimulation of other moda lities,The functional significance of this crossmodal activation was recent ly indicated by,for example, studies showing that the occipital cortex of t he blind is activated by sound changes, when the task is to detect these ch anges, Moreover, transcranial magnetic stimulation applied to the occipital cortex of blind individuals results in distortions and omissions of letter s in Braille text being read by the subject, Contrary to prevailing views, crossmodal neural reorganization might, as shown by recent results, take pl ace even in the mature human brain.