Facile regioselective synthesis of 1,2,6,8-tetraazaspiro[4.4]nona-2,6-dien-9-ones

Authors
Girgis, AS
Citation
As. Girgis, Facile regioselective synthesis of 1,2,6,8-tetraazaspiro[4.4]nona-2,6-dien-9-ones, Z NATURFO B, 55(2), 2000, pp. 222-226
Citations number
24
Categorie Soggetti
Chemistry
Journal title
ZEITSCHRIFT FUR NATURFORSCHUNG SECTION B-A JOURNAL OF CHEMICAL SCIENCES
ISSN journal
09320776 → ACNP
Volume
55
Issue
2
Year of publication
2000
Pages
222 - 226
Database
ISI
SICI code
0932-0776(200002)55:2<222:FRSO1>2.0.ZU;2-N
Abstract
1,3-Dipolar cycloaddition reaction of nitrilimines to a variety of 3-aryl-5 -arylmothylidene-3,5-dihydro-2-phenyl-4N-imidazol-4-ones (3) afforded the c orresponding 1,3,4,7,8-pentaaryl-1,2,6,8-tetraazaspiro[4,4]-nona-2,6-dien ( 4) and not the regio-isomers 2,3,6,8,9-pentaaryl-1,3,7,8-tetraazaspiro[4,4] nona-1,6-dien-4-ones (5) in high regioselectivity.