Dedifferentiated chondrosarcoma of the larynx

A 74-year-old man with a history of a chondroid lesion of the larynx noted an enlarging neck mass. Axial CT showed a large expansile lesion arising fr om the left thyroid cartilage. Multiple rings and arcs with relatively inta ct cortex indicated a chondroid lesion, Irregularity of the anterolateral m argin abutted a prominent soft-tissue component. The specimen obtained from fine needle aspiration was suggestive of a malignant fibrous histiocytoma, After further resection, the final diagnosis was dedifferentiated chondros arcoma, A new soft-tissue component or rapid growth of the mass can be indi cative of a diagnosis of dedifferentiated chondrosarcoma.