A CONVENIENT SYNTHESIS OF MONPAIN TRIMETHYLETHER

Authors
BEKAERT A ANDRIEUX J PLAT M BRION JD
Citation
A. Bekaert et al., A CONVENIENT SYNTHESIS OF MONPAIN TRIMETHYLETHER, Tetrahedron letters, 38(24), 1997, pp. 4219-4220
Citations number
10
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron letters → ACNP
ISSN journal
00404039
Volume
38
Issue
24
Year of publication
1997
Pages
4219 - 4220
Database
ISI
SICI code
0040-4039(1997)38:24<4219:ACSOMT>2.0.ZU;2-T
Abstract
A high yield synthesis of various 2-hydroxy-1,4-naphtoquinones was ach ieved by SeO2 oxidation of 1-tetralones into the corresponding 1,2-qui nones, followed by heterogeneous phase KO2 mediated oxidation. Applica tion of this synthesis to 5,7,8-trimethoxy-1-tetralone gave 2-hydroxy- 5,7,8-trimethoxy-1,4-naphtoquinone 3d or monpain trimethylether. (C) 1 997 Elsevier Science Ltd.