Breast lymphoma is a rare disease. Both primary and secondary breast involv
ement have been reported. Most primary breast lymphomas are high-grade mali
gnant neoplasms, mainly large cell and Burkitt type. Low-grade lymphomas of
the breast, particularly mucosa-associated lymphoid tissue (MALT) lymphoma
s, have been exceedingly rare. In this report we present a patient with bil
ateral breast involvement by MALT lymphoma. Our patient developed localized
MALT lymphoma in both breasts in a sequential fashion. She was treated wit
h bilateral lumpectomy, followed by radiation therapy to both breasts. The
patient is alive and well more than 1 year after therapy with no recurrence
. We believe this is the first such case described in detail in the literat
ure.