Sewage workers are exposed to a wide range of chemicals and biological agen
ts, including the hepatitis A virus. Inasmuch as Israel is an endemic area
for hepatitis A, it is unclear if sewage workers are at increased risk for
hepatitis A or which factors contribute to such risk. The authors compared
seropositivity of hepatitis A in 100 sewage workers with that in 100 blue-c
ollar worker controls. Hepatitis A seropositivity was highly prevalent, but
nonsignificant, in both sewage workers and controls (82% and 91%, respecti
vely). In sewage workers, the major risk for serological positivity was age
(odds ratio = 4.5, 95% confidence interval = 1.6, 12.4 for every 10 y). Th
e factors associated negatively with seropositivity were years of education
and years of seniority. The authors concluded that exposure to sewage is n
ot a risk factor for hepatitis A infection in Israel, and, therefore, sewag
e workers do not require special attention in this regard.