Phytosorbent prepared from sunflower seed husks prevents mercuric chlorideaccumulation in kidney and muscle of adult rabbits

Citation
Va. Lapina et al., Phytosorbent prepared from sunflower seed husks prevents mercuric chlorideaccumulation in kidney and muscle of adult rabbits, ARCH ENV HE, 55(1), 2000, pp. 48-50
Citations number
16
Categorie Soggetti
Environment/Ecology,"Pharmacology & Toxicology
Journal title
ARCHIVES OF ENVIRONMENTAL HEALTH
ISSN journal
00039896 → ACNP
Volume
55
Issue
1
Year of publication
2000
Pages
48 - 50
Database
ISI
SICI code
0003-9896(200001/02)55:1<48:PPFSSH>2.0.ZU;2-T
Abstract
In the present study, the effect of a melanin-containing phytosorbent, "Vic toria," on mercury accumulation in rabbits' tissues was studied. This phyto sorbent is derived from black sunflower seed husks. Domestic rabbits were a dministered either one single nontoxic low-level dose of mercuric chloride (i.e., 50 mu g/l kg body weight [control group]) or combinations of mercury and the phytosorbent "Victoria" (i.e., experimental group). Mercury and ph ytosorbent were administered per os daily for 12 d. Mercury in tissues was determined by cold-vapor atomic absorption spectroscopy. Mercury in kidney and muscle of the experiment group was, on average, 25.8 and 4.7 times less , respectively, than in the control group. The authors concluded that the p hytosorbent prevented accumulation of mercury in the kidney and muscle tiss ues and exerted a protective effect against mercury toxicity.