Resistance-modifying agents. Part 7: 2, 6-disubstituted-4,8-dibenzylaminopyrimido[5,4-d]pyrimidines that inhibit nucleoside transport in the presenceof alpha(1)-acid glycoprotein (AGP)
Hc. Barlow et al., Resistance-modifying agents. Part 7: 2, 6-disubstituted-4,8-dibenzylaminopyrimido[5,4-d]pyrimidines that inhibit nucleoside transport in the presenceof alpha(1)-acid glycoprotein (AGP), BIOORG MED, 10(6), 2000, pp. 585-589
The synthesis and biological evaluation of potent 4,8-dibenzylaminopyrimido
pyrimidine nucleoside transport inhibitors, with reduced binding to alpha(1
)-acid glycoprotein, is reported. (C) 2000 Elsevier Science Ltd. All rights
reserved.