Resistance-modifying agents. Part 7: 2, 6-disubstituted-4,8-dibenzylaminopyrimido[5,4-d]pyrimidines that inhibit nucleoside transport in the presenceof alpha(1)-acid glycoprotein (AGP)

Citation
Hc. Barlow et al., Resistance-modifying agents. Part 7: 2, 6-disubstituted-4,8-dibenzylaminopyrimido[5,4-d]pyrimidines that inhibit nucleoside transport in the presenceof alpha(1)-acid glycoprotein (AGP), BIOORG MED, 10(6), 2000, pp. 585-589
Citations number
19
Categorie Soggetti
Chemistry & Analysis
Journal title
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
ISSN journal
0960894X → ACNP
Volume
10
Issue
6
Year of publication
2000
Pages
585 - 589
Database
ISI
SICI code
0960-894X(20000320)10:6<585:RAP726>2.0.ZU;2-Y
Abstract
The synthesis and biological evaluation of potent 4,8-dibenzylaminopyrimido pyrimidine nucleoside transport inhibitors, with reduced binding to alpha(1 )-acid glycoprotein, is reported. (C) 2000 Elsevier Science Ltd. All rights reserved.