Pyrrolidine as a cogwheel-like scaffold for the deployment of diverse functionality through cycloaddition reactions of metallo-1,3-dipoles in aqueousmedia

Authors
Hanessian, S Bayrakdarian, M
Citation
S. Hanessian et M. Bayrakdarian, Pyrrolidine as a cogwheel-like scaffold for the deployment of diverse functionality through cycloaddition reactions of metallo-1,3-dipoles in aqueousmedia, BIOORG MED, 10(5), 2000, pp. 427-431
Citations number
43
Categorie Soggetti
Chemistry & Analysis
Journal title
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
ISSN journal
0960894X → ACNP
Volume
10
Issue
5
Year of publication
2000
Pages
427 - 431
Database
ISI
SICI code
0960-894X(20000306)10:5<427:PAACSF>2.0.ZU;2-M
Abstract
The reaction of glycinatocopper complexes with cinnamaldehydes under mildy basic aqueous conditions, affords polysubstituted prolines, which can be sy stematically modified in a number of chemoselective transformations. (C) 20 00 Elsevier Science Ltd. All rights reserved.