A clinical study on the efficacy of two commercial veterinary pramoxine cream rinses in the management of pruritus in atopic dogs

Pramoxine hydrochloride is a local anesthetic that has ben used in dogs for the topical management of pruritus. To our knowledge, there have been no p ublished clinical studies on its use as an adjunctive drug in the managemen t of pruritus in atopic dogs. We conducted an open clinical trial on the us e of two veterinary pramoxine cream rinses in 17 dogs with pruritus due to atopy. After 4 weeks, the owners of these dogs were asked to evaluate their pets for response and adverse effects. They reported that these products w ere effective in seven dogs and not effective in ten dogs. Six dogs experie nced increased pruritis after application of the product. Although this as a small study, pramoxine cream causes may be a useful therapeutic adjunct i n the management of pruritus in certain atopic dogs.