Research on the origin of life: Membrane-assisted polycondensations of amino acids and peptides

Authors
Luisi, PL Walde, P Blocher, M Liu, DJ
Citation
Pl. Luisi et al., Research on the origin of life: Membrane-assisted polycondensations of amino acids and peptides, CHIMIA, 54(1-2), 2000, pp. 52-53
Citations number
8
Categorie Soggetti
Chemistry
Journal title
CHIMIA
ISSN journal
00094293 → ACNP
Volume
54
Issue
1-2
Year of publication
2000
Pages
52 - 53
Database
ISI
SICI code
0009-4293(2000)54:1-2<52:ROTOOL>2.0.ZU;2-O
Abstract
The question as to whether and to what extent the phospholipid membrane of liposomes can assist in the polymerization of amino acids and peptides has been investigated. It has been found that the membrane can select hydrophob ic amino acids and peptides, thus operating as a selection tool in the poly merization reaction and thus permitting the formation of oligopeptides not possible in water- in the absence of liposomes - as a result of the too low solubility.