Microbial reduction of sulfur-containing ketones by Geotrichum sp.

Citation
Zl. Wei et al., Microbial reduction of sulfur-containing ketones by Geotrichum sp., CHIN J CHEM, 18(2), 2000, pp. 249-251
Citations number
13
Categorie Soggetti
Chemistry
Journal title
CHINESE JOURNAL OF CHEMISTRY
ISSN journal
1001604X → ACNP
Volume
18
Issue
2
Year of publication
2000
Pages
249 - 251
Database
ISI
SICI code
1001-604X(200003/04)18:2<249:MROSKB>2.0.ZU;2-4
Abstract
Bioreduction of some beta-carbonyl phenyl sulfides, sulfoxides and sulfones (1, 3, 5, 8, 11 and 13) by Geotrichum sp. was studied. Reduction of beta-c arbonyl phenyl sulfoxides (5 and 8) gave anti-Prelog sulfoxide alcohols. (S ,S-s)-3-Chloro-1-phenylsulfinylpropan-2-ol (9) was obtained in high yield w ith 95% e. e. after recrystallization from methylene chloride-petroleum eth er.