Type 2 diabetes mellitus and large vessel disease

Meal and post-meal period define the postprandial state, which overall cove rs a little bit more than half daytime period. The post-prandial state is c haracterized by transient plasma variations in carbohydrates, lipids and ho rmones in direct relation with nutrient intake. These variations have an im pact on the metabolism of several tissues. The post-prandial state in type 2 diabetic patients is considered as a cruc ial period, mainly due to the tissular toxicity of glucose. The established links between hyperglycemia and the rise of triglycerides-enriched particu les can favor atherogenesis.