We compare simultaneous versus sequential moves in R&D decisions within an
asymmetric R&D/Cournot model with linear demand (for differentiated product
s), general R&D costs, and spillovers. Simultaneous play and sequential pla
y (with and without a specified leader) can emerge as appropriate formulati
ons, depending on the ratios of spillover rate over demand cross-slope, but
not on R&D efficiency. When at least one ratio is above 1/2, a sequential
solution mitigates competition and leads to higher profits for each firm, a
nd to higher social welfare. When uniquely specified, the stronger firm eme
rges as the R&D first-mover.